<!DOCTYPE html>
<html lang="en">

<head>
  <meta charset="UTF-8">
  <meta name="viewport" content="width=device-width, initial-scale=1.0">
  <meta http-equiv="X-UA-Compatible" content="ie=edge">
  <title>全屏布局</title>
  <style>
    html,
    body {
      margin: 0;
      overflow: hidden;
    }
    header {
      height: 100px;
      position: fixed;
      top: 0;
      left: 0;
      right: 0;
      background-color: lightgray;
    }
    .content {
      position: fixed;
      left: 0;
      right: 0;
      top: 100px;
      bottom: 100px;
      overflow: auto;
      background-color: lightblue;
    }

    .content .left {
      width: 300px;
      height: 100%;
      position: fixed;
      left: 0;
      top: 100px;
      bottom: 100px;
      background-color: lightcoral;
    }

    .content .right {
      height: 1000px;
      margin-left: 300px;
      background-color: greenyellow;
    }

    footer {
      height: 100px;
      position: fixed;
      bottom: 0;
      left: 0;
      right: 0;
      background-color: lightslategray;
    }
  </style>
</head>

<body>
  <header></header>
  <div class="content">
    <div class="left"></div>
    <div class="right"></div>
  </div>
  <footer></footer>
</body>
</html>